As we age, collagen, elastin, and subcutaneous fat, which support and give volume to the skin, decrease. This leads to skin sagging, wrinkles, and the formation of hollow areas or atrophy, especially in regions such as the cheeks, facial contours, and lips.
Volume loss in the body refers to a decrease in natural fullness and firmness in areas such as the arms, thighs, buttocks, and abdomen. This loss is mainly caused by the reduction of subcutaneous fat, muscle mass loss, and decreased skin elasticity.